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The Crowned MD Dr Aliya Frederick

Dr. Aliya Frederick, MD, PhD

THE PHYSICIAN AND THE SCIENTIST

Excellence at the Intersection of Medicine and Science.

Dr. Frederick is a Pediatric Neurologist at Rady Children's Hospital and UC San Diego, where she serves on faculty as an Assistant Professor of Pediatrics and Neurology, specializing in Clinical Neurophysiology and Headache Medicine. 

Her clinical expertise spans pediatric neurology and neurophysiology, and her academic background in neuroscience informs both her practice and her passion for making science accessible, exciting, and achievable for young people who are just beginning to imagine their own futures in medicine.​​​

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​Areas of Expertise

  • Pediatric Headache & Migraine 

  • Pediatric Epilepsy

  • Clinical Neurophysiology & EEG

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  • Neuromodulation

  • Clinical Research

  • Medical Education

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​​License

 

CA State Medical License since 2017

Board Certifications

 

American Board of Psychiatry and Neurology

  • Neurology with Special Qualification in Child Neurology

  • Clinical Neurophysiology

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THE AUTHOR & EDUCATOR

Making Pediatric Neurology Accessible to Families

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Migraine Overview
A family-friendly overview of migraine in children, including symptoms, diagnosis, treatment, and support.

*Written for the Child Neurology Foundation

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Children’s Migraine Book
A child-friendly guide designed to help young patients understand migraine and what to expect when visiting a neurologist.

Active Research and Clinical Studies

  • Phase 3, multicenter, randomized, double-blind, group sequential, placebo-controlled study to assess efficacy and safety of rimegepant for the treatment of migraine (with or without aura) in children and adolescents ≥ 6 to <18 years of age

 

  • Phase 3, multicenter, open-label study to assess the long-term safety and tolerability of rimegepant for the acute treatment of migraine (with or without aura) in children and adolescents ≥ 6 to < 18 years of age

 

  • Enhancing Hair Care in the Pediatric Healthcare Setting: Improving Access, Training, and Resources for Inclusive Hair Care

Selected Publications

2026

Vigabatrin Versus Adrenocorticotropic Hormone After High-Dose Prednisolone Failure for the Treatment of Epileptic Spasms

 

Journal of Child Neurology

2026 Mar; 41(3):359-364. Layton A, Sattar S, Rho JM, Yang JH, Gold J, Zimbric MBui JSahagian M, Kim-McManus O, Frederick AGuido-Estrada NJindal AWiegand SDove KSweat MNespeca M, Montenegro MA

2025​​

Laser Interstitial Thermal Therapy for the Treatment of Mesial Temporal Lobe Epilepsy in Children.

 

Journal of Child Neurology

2025 May; 40(5):342-347. Trivedi AM, Montenegro MA, Gonda D, Kim-McManus O, Rismanchi N, Frederick AGuido-Estrada NJindal ASattar S.

2022

Expanding the phenotypic and molecular spectrum of NFS1-related disorders that cause functional deficiencies in mitochondrial and cytosolic iron-sulfur cluster containing enzymes.

 

Human Mutation

2022 03; 43(3):305-315. Yang JH, Friederich MW, Ellsworth KA, Frederick A, Foreman E, Malicki D, Dimmock D, Lenberg J, Prasad C, Yu AC, Anthony Rupar C, Hegele RA, Manickam K, Koboldt DC, Crist E, Choi SS, Farhan SMK, Harvey HSattar S, Karp N, Wong THaas R, Van Hove JLK, Wigby KWigby K.

2021

To Be or No B2: A Rare Cause of Stridor and Weakness in a Toddler

 

Child Neurology Open

2021 Jan-Dec; 8:2329048X211030723. Frederick ALYang JH, Schneider S, Quade A, Guidugli L, Wigby KWigby KCameron M

Triacetyluridine treats epileptic encephalopathy from CAD mutations: a case report and review.

Annals of Clinical and Translational Neurology 

2021 01; 8(1):284-287. Frederick ASherer K, Nguyen L, Ali S, Garg A, Haas RSahagian MBui J

2020

Electroencephalographic Findings in Pediatric Patients with Anti-N-Methyl-D-Aspartate Receptor Encephalitis: The San Diego Experience.

 

Journal of Pediatric Epilepsy

2020. Aliya Frederick , J. Yang , N, Guido-Estrada , J, Soria-Lopez , S. Sattar.

2015

Evidence against dopamine D1/D2 receptor heteromers.

 

Molecular Psychiatry

2015 Nov; 20(11):1373-85. Frederick AL, Yano H, Trifilieff P, Vishwasrao HD, Biezonski D, Mészáros J, Urizar E, Sibley DR, Kellendonk C, Sonntag KC, Graham DL, Colbran RJ, Stanwood GD, Javitch JA.

2012

Neurobehavioral phenotyping of G(αq) knockout mice reveals impairments in motor functions and spatial working memory without changes in anxiety or behavioral despair.

Frontiers in Behavioral Neuroscience

2012; 6:29. Frederick AL, Saborido TP, Stanwood GD. 

2009

Drugs, biogenic amine targets and the developing brain.

 

Developmental Neuroscience

2009; 31(1-2):7-22. Frederick AL, Stanwood GD.

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