Dr. Aliya Frederick, MD, PhD
THE PHYSICIAN AND THE SCIENTIST
Excellence at the Intersection of Medicine and Science.
Dr. Frederick is a Pediatric Neurologist at Rady Children's Hospital and UC San Diego, where she serves on faculty as an Assistant Professor of Pediatrics and Neurology, specializing in Clinical Neurophysiology and Headache Medicine.
Her clinical expertise spans pediatric neurology and neurophysiology, and her academic background in neuroscience informs both her practice and her passion for making science accessible, exciting, and achievable for young people who are just beginning to imagine their own futures in medicine.

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Areas of Expertise
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Pediatric Headache & Migraine
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Pediatric Epilepsy
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Clinical Neurophysiology & EEG
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Neuromodulation
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Clinical Research
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Medical Education
License
CA State Medical License since 2017
Board Certifications
American Board of Psychiatry and Neurology
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Neurology with Special Qualification in Child Neurology
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Clinical Neurophysiology

THE AUTHOR & EDUCATOR
Making Pediatric Neurology Accessible to Families
Migraine Overview
A family-friendly overview of migraine in children, including symptoms, diagnosis, treatment, and support.
*Written for the Child Neurology Foundation
Children’s Migraine Book
A child-friendly guide designed to help young patients understand migraine and what to expect when visiting a neurologist.
Active Research and Clinical Studies
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Phase 3, multicenter, randomized, double-blind, group sequential, placebo-controlled study to assess efficacy and safety of rimegepant for the treatment of migraine (with or without aura) in children and adolescents ≥ 6 to <18 years of age
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Phase 3, multicenter, open-label study to assess the long-term safety and tolerability of rimegepant for the acute treatment of migraine (with or without aura) in children and adolescents ≥ 6 to < 18 years of age
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Enhancing Hair Care in the Pediatric Healthcare Setting: Improving Access, Training, and Resources for Inclusive Hair Care
Selected Publications
2026
Journal of Child Neurology
2026 Mar; 41(3):359-364. Layton A, Sattar S, Rho JM, Yang JH, Gold J, Zimbric M, Bui J, Sahagian M, Kim-McManus O, Frederick A, Guido-Estrada N, Jindal A, Wiegand S, Dove K, Sweat M, Nespeca M, Montenegro MA
2025
Laser Interstitial Thermal Therapy for the Treatment of Mesial Temporal Lobe Epilepsy in Children.
Journal of Child Neurology
2025 May; 40(5):342-347. Trivedi AM, Montenegro MA, Gonda D, Kim-McManus O, Rismanchi N, Frederick A, Guido-Estrada N, Jindal A, Sattar S.
2022
Human Mutation
2022 03; 43(3):305-315. Yang JH, Friederich MW, Ellsworth KA, Frederick A, Foreman E, Malicki D, Dimmock D, Lenberg J, Prasad C, Yu AC, Anthony Rupar C, Hegele RA, Manickam K, Koboldt DC, Crist E, Choi SS, Farhan SMK, Harvey H, Sattar S, Karp N, Wong T, Haas R, Van Hove JLK, Wigby K, Wigby K.
2021
To Be or No B2: A Rare Cause of Stridor and Weakness in a Toddler
Child Neurology Open
2021 Jan-Dec; 8:2329048X211030723. Frederick AL, Yang JH, Schneider S, Quade A, Guidugli L, Wigby K, Wigby K, Cameron M.
Triacetyluridine treats epileptic encephalopathy from CAD mutations: a case report and review.
Annals of Clinical and Translational Neurology
2021 01; 8(1):284-287. Frederick A, Sherer K, Nguyen L, Ali S, Garg A, Haas R, Sahagian M, Bui J.
2020
Journal of Pediatric Epilepsy
2020. Aliya Frederick , J. Yang , N, Guido-Estrada , J, Soria-Lopez , S. Sattar.
2015
Evidence against dopamine D1/D2 receptor heteromers.
Molecular Psychiatry
2015 Nov; 20(11):1373-85. Frederick AL, Yano H, Trifilieff P, Vishwasrao HD, Biezonski D, Mészáros J, Urizar E, Sibley DR, Kellendonk C, Sonntag KC, Graham DL, Colbran RJ, Stanwood GD, Javitch JA.
2012
Frontiers in Behavioral Neuroscience
2012; 6:29. Frederick AL, Saborido TP, Stanwood GD.
2009
Drugs, biogenic amine targets and the developing brain.
Developmental Neuroscience
2009; 31(1-2):7-22. Frederick AL, Stanwood GD.


